The Mississippi River Delta is a vast national economic asset that is being squandered at tremendous cost. Over the last 80 years, the Delta has lost over 1.2 million acres of land, and the coastline has retreated by as much as 30 miles. Yet, this area is well worth the investment for restoration. This report presents the most comprehensive measure of the economic value of the Mississippi River Delta’s natural systems to date, demonstrating that the area’s ecosystems provide at least $12 to $47 billion in benefits to people each year. If this natural capital is treated as an economic asset, the Delta’s minimum asset value is $330 billion to $1.3 trillion. This study also examines the dynamic physical changes affecting the Delta region, outlines the economic implications of those changes, and compares three investment/restoration scenarios for the region.